came to report this exact problem and also solution which works
really should be patched at this point

Just got the ultimate edition and barely 2 hours or so in, immediately after finishing the Seer quest and visiting settlement the second time cannot proceed or do anything else. running on version 1.4.1.1
went through this thread (which is bit old and marked *solved*??), reddit, and bunch of other workarounds all to no avail. Ridiculous how this is still an issue (and seemingly i'm far from alone who faced it)
no issue with my controller and this is same for k+m, all in their default settings. even downloaded/reinstalled the whole game (100gb) twice at this point

Can anyone kindly guide me to an actual working solution please?

well damn, just got the ultimate edition last night to savour the full thing in one go (and with reasonable time until the next expansion releases) and now can't play past 2 hours lol
running version TU1.3 / in-game 1.4.1.1 and (so far) looks and works gorgeous on maxed out settings but half the controls don't work/show-up anymore. movement/camera and menu controls work but interaction, crouch, attacks don't so basically stuck and can't do anything apart from wandering around. this immediately happened once finished the seer quest and had to head back to the settlement for the literal second time.
looked all possible fixes, resetting controller/k+m, verifying etc but nothing works. how is this still an issue X__X
any solutions i could work/must have missed kindly suggest? using a ps4 controller on pc (via egs)